Keywords

• Venlafaxine
• 93413-69-5
• Factory price

Quick Details

• ProName: Factory Price Venlafaxine
• CasNo: 93413-69-5
• Molecular Formula: C17H27NO2
• Appearance: White Powder
• Application: Antidepressant, manic
• DeliveryTime: 15-20 days after receive the deposit
• PackAge: Bucket/Bottled/Bags
• Port: TianJin Or QingDao
• ProductionCapacity: 500 Metric Ton/Month
• Purity: 99%
• Storage: 2-8°C
• Transportation: By express(DHL,TNT,FedEx,UPS,and other...
• LimitNum: 1 Kilogram
• Related Substances: None
• Residue on Ignition: None
• Heavy Metal: None
• Valid Period: None

Superiority

Our Advantages:

1.We have abundant professional production experience.

2.We have our own chemical factory.

3.Sample is free of charge. 

4. Reasonable Price, Excellent Quality & Attentive Service 

5. Prompt reply: we can reply your inquiry and email within 24 hours.

6.Fast Delivery: The delivery time is about 10-20 days after receiving the deposit.

7. We have a unity cooperation team

Details

Product detail: 

Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.Target: SNRIVenlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. First introduced by Wyeth in 1993, now marketed by Pfizer, it is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. In 2007, venlafaxine was the sixth most commonly prescribed antidepressant on the U.S. retail market, with 17.2 million prescriptions.Venlafaxine is a bicyclic antidepressant, and usually categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI), but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It works by blocking the transporter "reuptake" proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. The neurotransmitters affected are serotonin and norepinephrine. Additionally, in high doses it weakly inhibits the reuptake of dopamine, with recent evidence showing that the norepinephrine transporter also transports some dopamine as well, since dopamine is inactivated by norepinephrine reuptake in the frontal cortex. The frontal cortex largely lacks dopamine transporters; therefore, venlafaxine can increase dopamine neurotransmission in this part of the brain. Venlafaxine interacts with opioid receptors (mu-, kappa1- kappa3- and delta-opioid receptor subtypes) as well as the alpha2-adrenergic receptor, and was shown to increase pain threshold in mice. When mice were tested with a hotplate analgesia meter (to measure pain), both venlafaxine and mirtazapine induced a dose-dependent, naloxone-reversible antinociceptive effect following intraperitoneal injection. These findings suggest venlafaxine's seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases.

Company information:

ShanLong Biotechnology Co., Ltd. is a high-tech enterprise specializing in high-tech and high value-added cosmetic raw materials, pharmaceutical intermediates, chemical customization, research and development, production and sales.

The company has its own R&D center and production base,Strong technical force, complete product testing methods and quality assurance system. The company not only has a group of high-tech talents engaged in the research and development, production, and management of pharmaceutical intermediates, but also makes full use of the technological and information advantages of scientific research units in universities, and has established long-term collaboration with pharmaceutical research institutes, large domestic pharmaceutical units and enterprises around the world Relationship, our products has been exported to Europe, Japan, South Korea, North America and other countries.

 

 

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