Shanlong Biotechnology (hebei) Co., Ltd. （expird）
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China (Mainland)
Business Type:Trading Company
CAS NO.78964-85-9
First class(1-499)KilogramFirst class(500-1000)KilogramHigh(1-499)Kilogram
Our Advantages:
1.We have abundant professional production experience.
2.We have our own chemical factory.
3.Sample is free of charge.
4. Reasonable Price, Excellent Quality & Attentive Service
5. Prompt reply: we can reply your inquiry and email within 24 hours.
6.Fast Delivery: The delivery time is about 10-20 days after receiving the deposit.
7. We have a unity cooperation team
Factory supply best price Fosfomycin tromethamine
Introduction
Fosfomycin tromethamine is a phosphonic acid bactericidal agent with in vitro activity against most urinary tract pathogens. It is particularly active against Escherichia coli, and Citrobacter, Enterobacter, Klebsiella, Serratia and Enterococcus spp. There appears to be little cross-resistance between fosfomycin and other antibacterial agents, possibly because it differs from other agents in its general chemical structure and site of action
Specification
| Items | Specifications | Results |
| Characteristics | White or almost white powder | Almost white powder |
| Identification | IR: Complies | Complies |
| Specific Rotation(anhydrous substance ) | -12.5°~-13.5° | -13.12° |
| Water | ≤0.5% | 0.15% |
| Acidity(pH ) | 3.5~5.5 | 4.88 |
| Heavy Metals | ≤0.0010% | <0.0010% |
| Phosphates | ≤0.0500% | <0.0500% |
| Related Substances | Impurity A: ≤0.3% | Not detected |
| Impurity B: ≤0.3% | 0.09% | |
| Impurity C: ≤0.1% | Not detected | |
| Impurity D: ≤0.1% | Not detected | |
| Unspecified impurity:≤0.1% | Not detected | |
| Total: ≤0.5% | 0.09% | |
| Residual Solvents | Methanol:≤0.3% | 0.10% |
| Methyl tert-butyl ether: ≤0.5% | 0.00% | |
| Assay | 98.0%~102.0% |
100.50% |
Function
Fosfomycin tromethamine is a bactericidal phosphonic acid derivative which acts primarily by inhibiting bacterial cell wall (peptidoglycan) synthesis. It has antibacterial activity against many pathogenic and opportunistic Gram-positive and Gram-negative bacteria isolated from patients with lower urinary tract infections (UTI). According to conventional in vitro susceptibility tests, fosfomycin has good activity against Escherichia coli, Staphylococcus aureus, and Serratia, Klebsiella, Citrobacter, Enterococcus and Enterobacter spp. Minimum inhibitory concentrations active against 90% of isolates (MIC90 values) for some other important pathogens are relatively high, but are well within the urinary concentrations of fosfomycin achieved during treatment with the drug.
About us
ShanLong Biotechnology Co., Ltd. is a high-tech enterprise specializing in high-tech and high value-added cosmetic raw materials, pharmaceutical intermediates, chemical customization, research and development, production and sales. The company has its own R&D center and production base. Strong technical force, complete product testing methods and quality assurance system. The company not only has a group of high-tech talents engaged in the research and development, production, and management of pharmaceutical intermediates, but also makes full use of the technological and information advantages of scientific research units in universities, and has established long-term collaboration with pharmaceutical research institutes, large domestic pharmaceutical units and enterprises around the world Relationship, our products has been exported to Europe, Japan, South Korea, North America and other countries.
ShanLong Biotechnology is committed to product research, development, and production, and pushes continuously innovative products to the global market. The company has always adhered to the business values of "quality for stability, innovation for development", reliable reputation, first-class service, and flexibility Pursuing long-term goals, sincere cooperation, mutual benefit and common development with colleagues in the chemical and pharmaceutical industries.
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