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Country: China (Mainland)
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CAS NO.104632-26-0
First class(1-499)KilogramFirst class(500-1000)Kilogram
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1.We have abundant professional production experience.
2.We have our own chemical factory.
3.Sample is free of charge.
4. Reasonable Price, Excellent Quality & Attentive Service
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6.Fast Delivery: The delivery time is about 10-20 days after receiving the deposit.
7. We have a unity cooperation team
Product detail:
Pramipexole is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS).Target: Dopamine Receptor Pramipexole also possesses low/insignificant affinity (500-10,000 nM) for the 5-HT1A, 5-HT1B, 5-HT1D, and α2-adrenergic receptors. It has negligible affinity (>10,000 nM) for the D1, D5, 5-HT2, α1-adrenergic, β-adrenergic, H1, and mACh receptors. All sites assayed were done using human tissues. While pramipexole is used clinically, its D3-preferring receptor binding profile has made it a popular tool compound for preclinical research. Pramipexole has been used (in combination with D2- and or D3-preferring antagonists) to interrogate the role of D3 receptor function in rodent models and tasks for neuropsychiatric disorders [1-3].
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