Business Type:Trading Company
Product Certification&
Enterprise Certification
Country: China (Mainland)
Business Type:Trading Company
CAS NO.516-54-1
First class(1-499)KilogramFirst class(500-1000)Kilogram
Our Advantages:
1.We have abundant professional production experience.
2.We have our own chemical factory.
3.Sample is free of charge.
4. Reasonable Price, Excellent Quality & Attentive Service
5. Prompt reply: we can reply your inquiry and email within 24 hours.
6.Fast Delivery: The delivery time is about 10-20 days after receiving the deposit.
7. We have a unity cooperation team.
Best quality Brexanolone/5alpha-Pregnan-3alpha-ol-20-one
Product Description
Allopregnanolone (ALLO), also known as 3α-hydroxy-5α-pregnan-20-one or 3α,5α-tetrahydroprogesterone (3α,5α-THP), is an endogenous inhibitory pregnane neurosteroid. It is synthesized from progesterone, and is a potent positive allosteric modulator of the action of gamma-amininobutyric acid (GABA) at GABAA receptor. Allopregnanolone has effects similar to those of other positive allosteric modulators of the GABA action at GABAA receptor such as the benzodiazepines, including anxiolytic, sedative, and anticonvulsant activity.
Endogenously produced allopregnanolone exerts a pivotal neurophysiological role by fine-tuning of GABAA receptor and modulating the action of several positive allosteric modulators and agonists at GABAA receptor. The 21-hydroxylated derivative of this compound, tetrahydrodeoxycorticosterone (THDOC), is an endogenous inhibitory neurosteroid with similar properties to those of allopregnanolone, and the 3β-methyl analogue of allopregnanolone, ganaxolone, is under development to treat epilepsy and other conditions, including post-traumatic stress disorder (PTSD).
About Us
ShanLong Biotechnology Co., Ltd. is a high-tech enterprise specializing in high-tech and high value-added cosmetic raw materials, pharmaceutical intermediates, chemical customization, research and development, production and sales. The company has its own R&D center and production base. Strong technical force, complete product testing methods and quality assurance system. The company not only has a group of high-tech talents engaged in the research and development, production, and management of pharmaceutical intermediates, but also makes full use of the technological and information advantages of scientific research units in universities, and has established long-term collaboration with pharmaceutical research institutes, large domestic pharmaceutical units and enterprises around the world Relationship, our products has been exported to Europe, Japan, South Korea, North America and other countries. ShanLong Biotechnology is committed to product research, development, and production, and pushes continuously innovative products to the global market. The company has always adhered to the business values of "quality for stability, innovation for development", reliable reputation, first-class service, and flexibility Pursuing long-term goals, sincere cooperation, mutual benefit and common development with colleagues in the chemical and pharmaceutical industries.
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